In addition to providing a highly organized framework, the ECM mediates signals to and from cells that are involved in important biological processes such as cell differentiation and migration ...

Mechanobiology is the scientific study of how cells recognize and respond to the mechanical properties of their surroundings.

Ongoing fundamental research on cancer cells could be used to create new drugs and therapies that fight the spread of cancer ...

In 2016, cancer biologist Johanna Joyce of the Memorial Sloan Kettering Cancer Center published a study in Science that ...

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...

Lipid peroxidation products are emerging as important stimuli to ECM production; their effects may be amplified by loss of antioxidant capacity of stellate cells as they activate. [30] These ...

TissueFab ®-Facile curable HA bioink also incorporates hyaluronic acid (HA), a natural polysaccharide present widely in the body and cellular ECM. Cells can recognize HA through surface receptors ...

Both the viscosity of the extracellular matrix and cell-cell interactions have a significant impact on how stem cells perceive their environment, a factor that should be taken into account when ...