uk-erlangen.de Background Osteophyte formation is a common phenomenon in arthritis. Bone formation by endochondral ossification is considered a key pathophysiological process in the formation of ...

invaded by vessels and ultimately replaced by bone through endochondral bone formation, the articular cartilage is permanent throughout life, is avascular and aneural and is resistant to calcification ...

We employ stem cell technologies or biomaterials advances with state-of-the-art regenerative technologies to recapitulate natural tissue development and regeneration. The majority of our research ...

Bone development is the formation and growth of bones. New bone is formed by the action of specialised cells called osteoblasts and osteoclasts, either by directly laying down bone tissue into ...

The study, published today (20 November) in Nature, shows a clear picture of how cartilage acts as a scaffold for bone development across the skeleton, apart from the top of the skull. The team ...

Credit: K. To, L. Fei, J. P. Pett, et al. (2024) A multiomic atlas of human early skeletal development. Nature. A new atlas maps human skeletal development, revealing key insights into bone formation, ...

Nov. 14, 2024 — Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic ... Vitamin D During ...

Bones that become damaged are replaced with new bone through a remodeling process that is largely dependent on dietary intake and lifestyle factors. Any imbalance to this remodeling process can lead ...