Excitatory amino-acid transporters (EAATs ... neuronal membranes also rapidly bind released glutamate to shape synaptic transmission. In this Review, we summarize the properties of glutamate ...

This study suggests that the FHM1 mutation leads to increased activity of presynaptic P/Q Ca 2+ channels, resulting in an imbalance between excitatory and inhibitory cortical transmission that ...

This results in enough neurotransmitter being diffused across the synaptic cleft to trigger the impulse in the postsynaptic neuron. This process is called summation.