Ischemic injury causes dynamic damage to the native extracellular matrix (ECM), which plays a ... injury to ischemic tissues is restoration of vascular function. Due to their potential to form ...

Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Fischell Department of Bioengineering, University of Maryland, College Park, Maryland 20742, United States ...

This study shows changes in microglia-vascular interactions in the context of heart failure, which unveils a novel potential therapeutic target for mitigating neuroinflammation in cardiovascular ...

Neurological disorders such as Alzheimer's and Parkinson's disease are among the most debilitating and life-altering ...

Hepatic fibrosis is a reversible wound healing response characterized by accumulation of extracellular matrix (ECM), or ... deposition of scar molecules, vascular and organ contraction, and ...

In the current issue of Arteriosclerosis, Thrombosis, and Vascular Biology, Zhang et al 3 took a molecular approach to characterize ... and increased production of ECM (extracellular matrix) ...

The abdominal aorta is a large artery in your belly that carries blood from the heart to the lower part of the body. In early fetal development, it forms from two smaller blood vessels, called the ...