Bitter taste receptor has hidden intracellular pocket that enables activation via simultaneous extracellular/intracellular ...

A new study describes an exciting discovery that changes the way we understand human bitter taste receptors. The research has ...

"Tasting Upside-Down - An Unusual Sensing Mechanism was Found in Human Bitter Sensing" A new study revealed that some bitter ...

Immunolabelling showed specific colocalisation of receptors with EEC mediators PYY and GLP-1 (L-cells) or 5-HT (enterochromaffin cells). We exposed isolated proximal colonic mucosa to specific ...

This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...

Adenosine A2A receptor activation regulates bone turnover, targetting bone destruction in inflammatory diseases like RA. The use of dipyridamole (blocks adenosine uptaken by the cells increasing ...

Scientists examine the effectiveness of an antibody targeting cell adhesion molecule 1 in alleviating pain-induced neuronal ...