eLife16 天
Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses ...
Department of Physiology, Harold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, United States ...
eLife20 天
SLC35G1 is a highly chloride-sensitive transporter responsible for the basolateral membrane ...
The cells were washed thrice with ice-cold PBS and fixed in 5% paraformaldehyde for 15 min. After washing thrice with PBS, the cells were incubated for 1 h at room temperature with an anti-human ...
Nature21 天
The antibodies don’t work! The race to rid labs of molecules that ruin experiments
He wondered whether a reagent was to blame, in particular the antibodies that scientists used to measure the amount of the protein and track its position in the cell. So, he and his colleagues ...
TechCrunch28 天
Archon emerges from stealth with $20M and ‘antibody cages’ to power up drug development
The company aims to supercharge antibody treatments using specially designed protein “cages” that multiply their effects, opening up new opportunities in drug development. The company was spun ...
GeekWire28 天
Archon Biosciences emerges from stealth with $20M to create tiny ‘Antibody Cages’
Ueda is holding an expandable toy that he uses to demonstrate how the company’s computationally designed Antibody Cages work. (GeekWire Photo / Alan Boyle) Three weeks after University of ...