Selfish DNA, like LINE-1, drives early human embryo development. Transposons, once seen as harmful, are essential for cell specialisation. LINE-1 helps organise DNA for smooth embryonic progression.
ALSO READ: Blame DNA, not diet: New study reveals the real reason behind gout When Dr Zhang inhibited LINE-1 expression in cultured human embryonic stem cells (ESCs), a reversal occurred ...
Inhibition of LINE-1 reverses the cells to the earlier 8C state, which has less green/red overlap (left). A critical transition in early human development is regulated not by our own genes, but by DNA ...
Zhang inhibited LINE-1 expression in cultured human embryonic stem cells (ESCs ... message molecules act as a scaffold to organize the DNA in the 3D space of the cell’s nucleus.