Belgian biopharma company UCB is bringing up the rear of the IL-17 inhibitor category with its bimekizumab drug, so is celebrating new late-stage data showing superiority to the class leader.

IL-17, IL-18, IL-23 and IL-32. Several reports now demonstrate a role for the ligand–receptor interaction of TL1A (also known as TNF ligand superfamily member 15) and DR3 in the pathogenesis of ...

Department of Immunology, Key Laboratory of Medical Molecular Virology (MOE, NHC, CAMS), School of Basic Medical Sciences, Department of Trauma-Emergency & Critical Care Medicine, Shanghai Fifth ...

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Sep. 9, 2024 — A research team has discovered when and why inflammatory signaling affects the formation of blood stem cells in embryos, which will benefit efforts to develop lab-grown ...

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Hypocrisy denounced; destruction of the Temple foretold; signs of Christ's return. Woe unto you, scribes and Pharisees, hypocrites! for ye devour widows' houses, and for a pretence make long prayer: ...

Conclusions RANKL expression and IL1β regulated MHC-class II, both induced via activation of the ERK1/2 signalling pathway, are specific for progenitor hBM-MSC expanded ... and the inhibitors UO126 ...

The adaptation of immune cells to their local microenvironments in our body is central to tissue homeostasis and linked to ...