invites aspiring scientists to join his lab to advance groundbreaking research in integrin transmembrane signaling, TGF-β activation, cell surface receptor mechanobiology, and therapeutic development.
Transmembrane proteins are integral to cell signaling and immune regulation. Antibodies can influence disease progression by binding to these proteins and either inhibiting or activating ...
We further examined the ligand-receptor interactions among these cell types and identified collagen as the top signaling pathway. Additionally, we investigated fibroblast function at different ...
Here, we use a genetic screen and proximity-dependent biotin identification to identify deubiquitinase(s) that control integrin surface levels ... the cytoplasmic tails of internalized Itgb1 and ...
Depletion of eIF3d or eIF3e, but not eIF3h reduced the levels of multiple components of the MAPK signaling pathways. Surprisingly, however, depletion of all three eIF3 subunits increased MAPK/ERK ...
Collagen XXIII is a type II transmembrane protein and the fourth in the subfamily of non-fibrillar transmembranous collagens. This kind of collagens have a single pass hydrophobic transmembrane domain ...