Researchers have analyzed the entire mouse intestine, mapping gene expression and cell states and location in the healthy gut and in response to perturbations such as inflammation. They identified ...
Jans and colleagues report compelling insights relevant to these questions by looking at how bacterial binding to cells lining the surface of the mouse colon amplifies colibactin-induced DNA ...
Here we report that Dickkopf-2 (DKK2) is essential for the generation of cancer cells with Paneth cell properties during colon cancer metastasis. Splenic injection of Dkk2-knockout (KO) cancer ...