Cell preparations were determined by FACS to contain 94% CD45 dim CD11b + microglia. The microglia were then treated with varying concentrations of recombinant IFNγ. WT microglia responded to ...

Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

This valuable study investigates the signaling pathways regulating retina regeneration. Solid evidence shows that the sphingosine-1-phosphate (S1P) signaling pathway is inhibited following retinal ...

1Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang-si, Republic of Korea. 2Immuno-Oncology Branch, Graduate School of Cancer Science ...

Department of Neuroscience, College of Medicine, The Ohio State University, Columbus, USA Campus Chemical Instrument Center, Mass Spectrometry & Proteomics Facility, The Ohio State University, ...

University of Washington-led research, published in 2023, discovered microglia in the brains of people with Alzheimer's disease were in a pre-inflammatory state more frequently, making them less ...

The Hebrew University team's metamodel brings these models together, drawing from data on how critical molecules—T-cell receptors (TCR), CD45, and Lck—interact and move at the initial points ...

Table 2. EV- surface epitopes with differential expression in tSCI and healthy controls. At the ER, the expressions of CD133+, CD45+, CD90+, CD68+, CX3CR1+, and CD196+ EVs were significantly ...

Understanding the intricacies of the brain tumor microenvironment (TME) is crucial for developing precise diagnostic and therapeutic strategies, but the high degree of complexity often limits research ...