Lack of NaV1.7 activity leads to the inability to sense pain, whereas NaV1.7 gain of function leads to severe pain. Modulation of NaV1.7, therefore, should be an effective mechanism for decreasing ...
Nearly 20 years ago, knowing all other options had failed, Nick’s sister, a nurse, recommended he check out a new treatment called vagus nerve stimulation, or VNS. The US Food and Drug ...