New research suggests previous assumptions about the pathogenesis of spinal muscular atrophy (SMA) are inadequate.

Children with severe SMA have substantial loss of motor and sensory neurons in the thoracic region of the spinal cord, a ...

A large, retrospective analysis of patients with amyotrophic lateral sclerosis (ALS) and progressive muscular atrophy (PMA) indicates that a substantial proportion of PMA patients develop upper ...

However, it's still unclear how this process causes neuron damage ... the mice to block remyelination and better mimic the pathology seen in human MS. The researchers studied two types of mouse ...

A decade ago, researchers introduced a new model for studying Alzheimer's disease. Known as "Alzheimer's in a dish," the model uses cultures of mature brain cells suspended in a gel to recapitulate ...

Researchers have created a highly detailed cellular map of Alzheimer’s disease progression, revealing new insights into the ...