There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, ...

This leads to ribosome production arrest and a potentially alternative way p14 ARF elicits its tumor suppressor function. “Upon overexpression, p14 ARF can go to the nucleolus and block ...

Through interaction with nucleophosmin, a protein abundant within the nucleolus that acts as director of the ribosome factory, p14 ARF becomes a spanner in the works of the nucleolus, disrupting ...

This occurs within the nucleolus, a membraneless compartment in the nucleus of cells responsible for ribosome production. In ...

"I think it's fascinating that an aspect of how p14 ARF acts as a tumor suppressor is through immobilization of the liquid-like nucleolus and apparent inhibition of critical steps in ribosome ...

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Investing.com -- Wall Street is seen slipping lower Friday, on course for weekly losses, after Fed chief Jerome Powell signaled a more patient approach to future interest rate cuts. Chinese ...