Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

a delayed clearance parathyroid hormone fusion polypeptide that is in preclinical trial for the treatment of chronic hypoparathyroidism; and AEZS-130 that is in preclinical trial for the treatment ...

July 24, 2024 — Surgeons compared traditional and new fully hydroxyapatite-coated hip replacement stems. They found the new stems offer larger contact areas, while traditional ones preserve bone ...

Sources of rare earth elements are frequently associated with volcanoes, dormant or otherwise. Here on Earth, rare-earth ...

Its product pipeline includes RT-102, a parathyroid hormone that is in Phase I clinical trial for the treatment of osteoporosis; RT-105, an anti-TNF-alpha antibody that is in preclinical studies ...

Part of Biology (Single Science) Cells, organ systems and ecosystems ...

Distinguishing ordinary diabetes from its monogenic forms has been one of the challenges in optimally managing the disease. Using high-quality imputation of rare variants and large databases, a ...