David Baker, Demis Hassabis and John M. Jumper revealed how amino acids shape protein structure, a finding that could aid in drug discovery Margherita Bassi Daily Correspondent David Baker ...

Nobel Prize in Physiology or Medicine has been awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

Systemic factors include hormones such as estrogen, which inhibits bone resorption by inducing osteoclast apoptosis and reducing the production of pro-resorptive cytokines; parathyroid hormone (PTH), ...

a delayed clearance parathyroid hormone fusion polypeptide that is in preclinical trial for the treatment of chronic hypoparathyroidism; and AEZS-130 that is in preclinical trial for the treatment ...

July 24, 2024 — Surgeons compared traditional and new fully hydroxyapatite-coated hip replacement stems. They found the new stems offer larger contact areas, while traditional ones preserve bone ...

Bone is a highly organized structure consisting of a protein matrix, primarily type 1 collagen, with hydroxyapatite mineral and cells from different lineages interspersed throughout. Skeletal tissue ...

Sources of rare earth elements are frequently associated with volcanoes, dormant or otherwise. Here on Earth, rare-earth ...

Its product pipeline includes RT-102, a parathyroid hormone that is in Phase I clinical trial for the treatment of osteoporosis; RT-105, an anti-TNF-alpha antibody that is in preclinical studies ...

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The most common surgeries to damage the RLN are thyroid and parathyroid surgery, because of how close the nerve is to the thyroid gland, which sits at the front of the throat. In fact, the RLN can ...

Part of Biology (Single Science) Cells, organ systems and ecosystems ...