Nature10 年
Kidney complications: Factors that protect the diabetic vasculature
The filtration barrier is supported by a core of mesangial cells, which resemble smooth muscle cells. Endothelial and podocyte functions are crucial for maintaining the filtration barrier ...
Medscape1 个月
From the Periphery of the Glomerular Capillary Wall Toward the Center of Disease
Although the pathophysiology of mesangial cells has long been considered to ... more recent evidence suggests that podocytes also play a critical role in the early functional and structural ...
Medscape15 天
From the Periphery of the Glomerular Capillary Wall Toward the Center of Disease
Alterations of mesangial cells have traditionally been the focus of research in deciphering molecular mechanisms of diabetic nephropathy. Injury of podocytes, if recognized at all, has been ...
University of Bristol7 年
Glomerular cell biology
Filtration is dependent on the unique structure of the capillary wall comprising layers of two key cells types, glomerular endothelial cells (GEnC) and podocytes, separated by a specialised basement ...
University of Bristol1 年
Human podocyte cell line
It is known and used worldwide by leading research groups and many of the world’s largest pharmaceutical companies. This conditionally immortalised human podocyte cell line was originally developed by ...