This is the first demonstration of the potential for small molecule intervention to modulate the RGS10 expression in microglia. RGS10 is transcriptionally silenced in vivo by endogenous inflammatory ...
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Microglia exhibit both maladaptive and adaptive roles in the pathogenesis of neurodegenerative ... Flat-mounted retinas were blocked for 1h in a blocking buffer containing 10% normal donkey serum and ...
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Primary insomnia is a condition characterized by difficulty sleeping. Unlike secondary insomnia, primary insomnia isn’t the result of medication side effects or medical or psychological problems. The ...
Louis. He thinks it offers a convincing explanation for why both microglia and ApoE seem to be needed to seed plaques. The study also underscores the primary role of lysosomal dysfunction in the ...