This valuable study addresses potential roles of the master regulator of X chromosome inactivation, the Xist long non-coding RNA, in autosomal gene regulation. Using data from mouse cells, the authors ...

Proteins were extracted from cells using RIPA buffer (Cold Spring Harbor Protocol 2017) supplied with 1 × Complete Protease Inhibitor Cocktail (Roche) and quantified with Pierce™ BCA Protein Assay Kit ...

Their new discovery is detailed in the paper, "Design of novel and highly selective SARS-CoV-2 main protease inhibitors," published in the journal Antimicrobial Agents and Chemotherapy.

Program for Cancer and Cell Biology, Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences; Peking University International Cancer Institute; and State Key Laboratory ...

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CEP192 also acts as an inhibitor of substrate phosphorylation through an allosteric mechanism based on its interaction with the F-pocket and the top of the R-spine. Structural characterisation of the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Becker muscular dystrophy (BMD) is an X-linked ...

Welcome to the cocktail heatmap, a running guide to the newest destinations for classic cocktails, frozen drinks, and rare spirits in New Orleans. Consider this map a guide to the hottest spots for ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study.