Mutations in a complex that helps proteins fold correctly are tied to developmental disorders that include seizures and intellectual disability, Stanford Medicine-led research has found.
The hydrophobic-polar protein folding model is a highly simplified model for examining protein folds in space. First proposed by Ken Dill in 1985, it is the most known type of lattice protein: it ...
Understanding the dynamic evolution of microscopic systems has been one of the biggest challenges in fundamental research, which plays a key role in areas like protein folding, drug development ...
High mutational load tumors mitigate effects from protein-damaging mutations by up-regulating complexes that buffer against misfolding stress, revealing therapeutic vulnerabilities and suggesting ...
One was working out how to efficiently manage magnetic fields that enable controlled nuclear fusion. The other involved understanding the mechanics of protein folding, and making good guesses about ...