NLRP3 inflammasome activation, pro-inflammatory cytokine production and pyroptosis are key features of inflammation that contribute to liver fibrosis progression, cirrhosis and end-stage liver failure ...

The team showed that MCC950 prevented the assembly of the NLRP3 inflammasome in mouse cells exposed to a bacterial toxin and blocked IL-1β secretion and cell death by pyroptosis. In mice ...

近日，中国科学院上海有机化学研究所生物与化学交叉研究中心许代超研究员在Cell Press细胞出版社期刊Trends in Cell Biology 发表了题为“Emerging roles of palmitoylation in pyroptosis ... 在NLRP3炎症小体 ...

ZyVersa Therapeutics (ZVSA) announces newly published data demonstrating that stroke-related cardiovascular injury and dysfunction is induced by AIM2 inflammasome activation and pyroptosis in the ...