However, somatic cells have little or no telomerase activity, gradually resulting in telomere attrition and cellular aging. Telomere length (TL) varies among individuals but steadily declines with ...
However, as cells divide, these telomeres shorten, ultimately leading to cellular aging and dysfunction. This connection between telomere length and aging has made them a focal point in longevity ...
Telomeres are repeated DNA sequences located at the ends of chromosomes and play an essential role in genome stability. They naturally shorten over time and are therefore involved in many biological ...
Furthermore, telomere shortening due to the inability of the DNA-replication machinery to fully replicate the ends is a critical mechanism of tumor suppression as well as a hallmark of aging.
Blackburn spoke to us about why this is, and how we can take better care of our telomeres to slow down the effects of aging. Blackburn co-authored "The Telomere Effect: A Revolutionary Approach to ...