Here, the authors report the synthesis of 5’-sulfonyl-4’-aryl-3-cyano substituted pyridazine compounds from a formal [4 + 2] reaction between vinylogous enaminonitriles and sulfonyl hydrazides.
High-throughput screening of the BMS internal compound collection identified the aryl dihydropyridinone compound 1 (hMGAT2 IC50 = 175 nM) as a hit. Compound 1 had moderate potency against human ...
Key Laboratory of Science and Technology of Eco-Textiles, Ministry of Education, College of Chemistry and Chemical Engineering, Donghua University, Shanghai 201620, People’s Republic of China ...
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Alcohols are organic compounds characterized by the presence of one or more hydroxyl (-OH) groups attached to a carbon atom. They play vital roles as building blocks in various chemical processes, ...
When you bite into a juicy hamburger, slice into the perfect medium-rare steak or gobble down a plateful of chicken nuggets, your senses are most likely responding to the food's smell, taste ...