This mechanism, which involves extracellular accumulation of a 56 kDa soluble amyloid-β (Aβ ... Their results suggest that other soluble protein assemblies could also have a role in inducing ...
This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).
A loss of brain volume associated with new immunotherapies for Alzheimer's disease may be caused by the removal of amyloid plaques, rather than the loss of neurons or brain tissue, finds a study led ...