The new Dogma meets Thomas Kuhn’s definition of a paradigm shift. The DNA/RNA Dogma is sufficiently unprecedented to attract ...

This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...

The assessment considered forecasts of power demand, planned upgrades to the transmission system, public policy and changes ...

当RNA病毒感染时，信号转接器MAVS会在线粒体外膜上形成功能性的聚集体，作为连接病毒与下游抗病毒天然免疫反应的中心枢纽。目前已有多种调节MAVS激活的机制，但控制MAVS聚集的检查点尚未被发现。2024年12月2日，来自中山大学生命科学学院崔隽教授 ...

A study led by the University of Barcelona and the Spanish National Research Council's Institute for Advanced Chemistry of ...

根据《自然通讯》的研究，当细菌暴露于广泛使用的抗生素中时，它们的核糖体会发生改变。经过修饰的核糖体在抗生素附着并停止蛋白质产生的区域发生了特殊的变化。研究发现，这使得细菌对药物的抵抗力更强。这些细微的变化可能足以改变药物靶点的结合位点，并可能构成抗生素耐药性的新机制。

A study led by the University of Barcelona and the Spanish National Research Council's Institute for Advanced Chemistry of Catalonia (IQAC - CSIC) presents a new therapeutic tool capable of inhibiting ...

NASA's latest findings reveal that RNA's role in life's preference for left-handed proteins may be less about chemical bias ...

This limits the wide impact of this study but can be used as a starting point to examine sex- and age differences in the transcriptome due to alternative splicing. Complex diseases often exhibit ...

日前，中美瑞康宣布其和蔡磊携手推进的第二款针对渐冻症（ALS）的小核酸药物RAG-21迎来新突破，成功获得美国食品药品监督管理局（FDA）授予的“孤儿药”资格。 “孤儿药”是什么？以渐冻症为代表的罕见病患者有救了吗？ 对此，中新社国是直通车在知乎上邀请到蔡磊及其团队，请他们以一名渐冻症抗争者的角度，分享这款“孤儿药”的研发相关经历。 什么是“孤儿药”？ 所谓“孤儿药”，是指针对罕见病开发的药物，一 ...

Cape Cod Healthcare will participate in a new national clinical research study focused on early detection of lung cancer with ...

EY Oceania chief economist Cherelle Murphy predicts the national accounts data set to be released on Wednesday to be “weak”.