By deducing the possible ancient forms of a bacterial enzyme, OIST scientists have resurrected one of its ancestral versions, ...

Belgium mRNA specialist Quantoom Biosciences and biologics manufacturing specialist Univercells inked a partnership deal with ...

This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...

Researchers investigate the influence of Mettl1 on energy metabolism and the maturation of heart cells after birth.

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

根据《自然通讯》的研究，当细菌暴露于广泛使用的抗生素中时，它们的核糖体会发生改变。经过修饰的核糖体在抗生素附着并停止蛋白质产生的区域发生了特殊的变化。研究发现，这使得细菌对药物的抵抗力更强。这些细微的变化可能足以改变药物靶点的结合位点，并可能构成抗生素耐药性的新机制。

Recent findings indicate that the chirality of molecules, critical to life's structure, might not have been as fixed in early ...

The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA ...

RNA是基因表达的直接产物，其动态变化对于细胞适应环境刺激具有重要意义。然而，传统的单细胞RNA测序技术仅能捕捉基因表达的静态快照，无法解析其动态变化。为解决这一难题，研究团队开发了Dyna-vivo-seq方法，将代谢标记物4sU注射至实验小鼠，通 ...

In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond ...

瑞典卡罗琳斯卡医学院等机构研究人员开发出一种突破性的显微镜方法，能够以细胞级分辨率对完整的小鼠大脑进行详细的三维RNA分析。发表在最新一期《科学》杂志上的这种名为TRISCO的新方法，有可能改变人们对正常和疾病状态下大脑功能的理解。