San Francisco’s star running back McCaffrey is sitting on injured reserve once again, with the postseason getting ever nearer ...

It seems as if the San Francisco 49ers have had the worst injury luck of any team in recent memory. Only a year removed from ...

Entering a do-or-die matchup vs. the Chicago Bears this Sunday, the San Francisco 49ers are banking on rookie running Isaac ...

RB Christian McCaffrey looked to finally be taking off after his return from an Achilles injury but suffered a PCL injury ...

San Fransisco 49ers running back Christian McCaffrey already missed the first eight games of the NFL season due to ...

San Francisco 49ers quarterback Brock Purdy addressed the team's heightened sense of urgency following recent challenges and shared his thoughts on the upcoming Week 14 matchup against the Chicago ...

The San Francisco 49ers have officially released updates on offensive tackle Trent Williams and defensive lineman Nick Bosa.

Cowboys legend and single-season rushing record holder Barry Sanders wished Boise State's Ashton Jeanty luck ahead of the ...

Jared Goff threw three touchdown passes and the Detroit Lions used their dominant offensive line to overwhelm the Green Bay ...

Guerendo has steadily improved this season and will step up in Christian McCaffrey and Jordan Mason's absence.

It would appear Christian McCaffrey's 2024 campaign is ending less than a month after it began. San Francisco 49ers head coach Kyle Shanahan told reporters after Sunday night's game that McCaffrey ...

San Francisco 49ers running back Christian McCaffrey has faced significant setbacks this season. After missing the first ...