And when Chicago reached the end zone, Williams dropped back on third-and-goal to hit fellow rookie Rome Odunze on an out ...

Rookie running back Isaac Guerendo left late in the fourth quarter of the 49ers' 38-13 win over the Chicago Bears with what most likley is a high ankle ...

SANTA CLARA — Before Christian McCaffrey arrived in 2022, the 49ers under coach Kyle Shanahan were largely a platoon ...

Isaac Guerendo will make his first NFL start on Sunday as the injury-depleted San Francisco 49ers face the Chicago Bears. The ...

No Christian McCaffrey has been no problem for the 49ers in the first quarter of Sunday's game against the Bears.

San Francisco 49ers safety Talanoa Hufanga, defensive back Deommodore Lenoir and defensive lineman Jordan Elliott are set to ...

It's the final week of byes and also the swan song for the regular season in some fantasy leagues, making for an intriguing ...

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve and is likely out for the season after suffering a PCL injury in Week 13 agai ...

Now with Christian McCaffrey and Jordan Mason out with injuries for San Francisco, that could all change with Guerendo set to ...

RB Christian McCaffrey looked to finally be taking off after his return from an Achilles injury but suffered a PCL injury ...

With Christian McCaffrey on the shelf, the 49ers will turn to RB Isaac Guerendo, and he will deliver in Week 14 against the Bears!

Both of these teams are nowhere near where they'd like to be this season, but with one finding a rejuvenated energy to themselves with a coaching change, here are three reasons for optimism for the ...