在一项新的研究中,来自德克萨斯大学西南医学中心的研究人员发现tRNA 可以决定 ...
撰文丨王聪编辑丨王多鱼排版丨水成文众所周知,根据中心法则,DNA转录为mRNA,mRNA再翻译为蛋白质,mRNA的降解速率是每个基因产生的蛋白质的数量的主要决定因素,而这又会影响细胞功能。例如,对于mRNA疫苗,mRNA存在更长时间会产生更多蛋白质,从而更好地激活免疫系统以抵抗感染;而对于CRISPR-Cas9基因编辑,产生Cas9蛋白 ...
科学家发现,转运 RNA (tRNA) 能够决定信使 RNA(mRNA)在细胞中的寿命,导致某些 mRNA 被稳定保存并翻译成更多的蛋白质,而另一些 mRNA 则被降解,从而限制蛋白质的生成量。
Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized ...
Fred Hutch researcher wins a $1M grant for a London-Seattle collaboration to find new therapies for drug-resistant prostate ...
Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA -- that molecular blueprint for life -- over 70 years ago. Today, scientists are still uncovering new ways to read it.
Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA -- that molecular blueprint for life -- ...
Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...