LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

In SNALPs, the backbone-modified siRNA is encapsulated within a closed shell of a cationic-zwitterionic lipid bilayer, furnished with an outer PEG shield (Figure 2A). The lipid bilayer contains a ...

Potent siRNAs against B4GALT1 were designed in silico and screened in vitro (Huh7 cells, primary mouse, human hepatocytes) as well as in vivo (C57BL/6 mice) for the selection of a lead Galomic siRNA.

At the American Heart Association’s Scientific Sessions, E-Therapeutics plc presented preclinical data for ETX-258, a Galomic siRNA being developed for the treatment of heart failure.

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

Researchers from Ludwig Maximilian University of Munich presented a study in Nano Letters on the molecular organization of ...

Researchers at Tel Aviv University have developed an effective, inexpensive, and simple COVID-19 vaccine that can be stored ...

Cross-species host–pathogen or mutualistic RNA communication, especially through extracellular vesicles, can have important applications, including gene silencing in agriculture and RNA-based ...

RNA therapeutics promise rapid, personalized and flexible treatments against multiple diseases. In this article, we will ...