As of Oct. 19, the San Francisco 49ers' odds of winning the Super Bowl (+700) make them second-best in the league. The 49ers knocked off the Seattle Seahawks 36-24 in their last game. Brock Purdy ...

Head coach Kyle Shanahan said Monday that the 49ers are hopeful Kittle (hamstring) returns to practice this week, Eric Branch of the San Francisco Chronicle reports. Kittle was a mid-week addition ...

For years, the San Francisco 49ers’ defensive line was easily the most feared part of an impenetrable defense. But for the second straight season, it’s a focal point of the team’s downward ...

The San Francisco 49ers will wear alternate uniforms that include white pants as they prepare for what promises to be the hottest NFL game played at Levi’s Stadium. Temperatures are expected to ...

For most of Shanahan’s tenure in the Bay, the San Francisco 49ers have owned his buddy Sean McVay’s club. SoFi Stadium on Sunday was, again, a sea of red. The hosts were winless and coming off ...

The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood. Related Articles San Francisco 49ers | Hold on, 49ers’ Nick Bosa isn’t ...

Without question, the best game of Week 8 is the San Francisco 49ers versus the Kansas City Chiefs. It is a rematch of Super Bowl LVIII, which is bound to generate excitement. These two teams have ...

INGLEWOOD -- The winless Los Angeles Rams were fresh off a 31-point loss and missing their top two receivers when they took the field Sunday against a rival that has dominated them for a half-decade.

The 49ers opened last NFL season on fire, winning their first five games before going into a three-game tailspin. This year, the rough patch has come early. Now, the 49ers are in desperate need of ...

The San Francisco 49ers needed a kicker right away after Jake Moody injured his ankle while making a tackle during Sunday’s loss, and the man they’ve signed to the job comes with quite the ...