Long-lasting changes to the cells’ epigenome are linked to a decline in their function. Even after drastic weight loss, the ...

A research team has identified an essential mechanism in fat cells (adipocytes) that enables them to enlarge safely to store ...

另一方面，表观遗传标记则更具动态性：环境因素、饮食习惯和身体状况（如肥胖）会在人的一生中改变这些标记。但它们可以保持稳定很多年，有时甚至几十年，在此期间，它们在决定哪些基因在细胞中活跃、哪些不活跃方面发挥着关键作用。

The biotechnology company, Obatala Sciences, developed ObaCell® Obesity-on-a-Chip technology that enables a more holistic ...

引言肥胖不只是一个简单的体重增加问题，更是一个牵涉广泛的代谢失调和慢性疾病的复杂现象。在过去的几十年中，全球肥胖率不断上升，使其成为威胁公众健康的主要问题之一。尽管许多人通过严格的饮食控制、运动干预、药物治疗，甚至减重手术成功减轻了体重，然而，随之而 ...

A CNIC study published in Nature Communications reveals that caveolae in adipocytes help safely store excess fat, preventing ...

Researchers at CNIC uncovered a vital role for caveolae in fat cell expansion. These membrane structures shield adipocytes ...

Obesity leads to DNA alterations that affect gene activity and linger after weight loss, a finding that researchers say could ...

Fat tissue may commit weight to memory. For people living with obesity, losing weight can help reduce the risk of health problems such as type 2 diabetes or cardiovascular disease (SN: 2/29/24). But ...

Epigenetic changes from obesity persist after weight loss, altering fat cell function and increasing the risk of weight ...

New studies in JACC highlight improvements in cardiac structure and function among CABG patients, as well as changes in ...

Men with cardiovascular disease risk factors such as type 2 diabetes, obesity, high blood pressure, and smoking may have ...