RNA splicing is a modification of the nascent ... into the regulatory mechanisms and therapeutic applications of alternative splicing. Interpreting the significance of putative splice-altering ...
Remix Therapeutics (Remix), a clinical-stage biotechnology company developing small molecule therapies to modulate RNA ...
By knocking down the expression of 305 spliceosome components and regulators in human cancer cells and employing deep RNA sequencing, the researchers monitored over 250,000 alternative splicing events ...
Dr. Silvi Rouskin's lab. Our research focuses on alternative RNA structures and the myriad of roles they have in both viral and human biology. Our lab is interested in alternative RNA structures and ...
Detailed map of the spliceosome is being made publicly available to help researchers pinpoint exactly where splicing errors ...
“Our study shows the potential of RNA editing to develop gene therapies that offer an alternative treatment to the invasive, frequent eye injections that are currently used to treat wet macular ...
Apr. 30, 2024 — A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found ...
THRAP3, STMN1, and GNA13—are overrepresented in blood cancers like acute myeloid leukemia (AML) and could prove to be novel ...
*仅供医学专业人士阅读参考常看今日说法之类节目的估计都知道,很多犯罪团伙是“家族式”的,基于各种亲情关系一起为非作歹,这就很像人体内的两种现象,一种是多个治疗靶点归属同一个家族,比如同属表皮生长因子受体家族的EGFR和HER2,另一种就是mRNA层面 ...