A recent study in Nature Neuroscience provides new insights into how amyloid-beta and tau proteins, which accumulate in the ...

A new study represents a significant step forward in scientists' understanding of Alzheimer's disease. A team of investigators has examined the role of two proteins found in the brain and suggest the ...

A new study from the University of Liverpool represents a significant step forward in scientists' understanding of Alzheimer's disease.

A new study from the University of Liverpool represents a significant step forward in scientists' understanding of ...

(IN BRIEF) Researchers at the University of Liverpool have identified a new mechanism in Alzheimer’s disease involving the ...

Behold the Body. Electron microgram of a Biondi body shows a dense core surrounded by filaments that bind gold-labeled secondary antibody to TMEM239 (black dots). [Courtesy of Ghetti et al., 2024.] ...

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).

Researchers have uncovered how certain genetic mutations lead to unique spherical amyloid plaques in inherited forms of ...

The pursuit of a cure for Alzheimer's disease is becoming an increasingly competitive and contentious quest with recent years ...

This important study identifies the "H-state" as a potential conformational marker distinguishing amyloidogenic from non-amyloidogenic light chains, addressing a critical problem in protein misfolding ...

Researchers have identified the structure of amyloid beta fibrils linked to a rare inherited form of Alzheimer’s disease ...