These statements include, but are not limited to, statements regarding the combination potential for MALT1 and BTK inhibitors in models of B-cell malignancies, PD biomarkers related to LSD1 ...

Poster Presentations Title: Combining next-generation BTK and MALT1 inhibitors to enhance efficacy and therapeutic utility in B-cell malignancies Session Title: Combination therapies Catalog ...

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“As our precision-designed LSD1 and MALT1 inhibitors continue to progress towards the clinic, we are excited to share new preclinical data from both programmes,” said David Hallett, Ph.D., interim ...

The French pharma said it will pay $100 per share in cash for San Francisco-based Principia, which specialises in Bruton’s kinase (BTK) inhibitor drugs, after the deal was unanimously agreed by ...

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Of the patients with preexisting CVD, those treated with first-generation BTK inhibitors had a greater chance of developing CVAEs, including atrial fibrillation. Preexisting cardiovascular disease ...

Monoamine oxidase inhibitors (MAOIs) are the oldest class of antidepressants. Although they have largely been replaced by newer medications with fewer side effects, they are still used to treat some ...

The Broad Institute of Harvard and MIT, Cambridge, Massachusetts. Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts. *Corresponding Author: Andrew J. Aguirre, Dana-Farber ...

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