Hepatitis B virus (HBV) has a narrow host range, mainly infecting hominoids. A new study reveals the structural differences in the liver cell receptor (NTCP) between humans and monkeys, explaining why ...

Cryo-electron microscopy reveals the structural basis for the restriction of hepatitis B virus (HBV) entry in macaques, ...

As well as having a role in lipid absorption, bile acids can act as endocrine-signaling molecules. With previous studies suggesting that bile acids operate as metabolic integrators, Watanabe et al.

A study reveals why monkeys resist HBV infection, showing that specific amino acid differences in their NTCP receptor prevent ...

An infection with the hepatitis B virus (HBV), which is spread by blood or bodily fluids, is one of the main causes of ...

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases, that spreads among individuals through blood or body fluids.

Odevixibat is a once-daily non-systemic ileal bile acid transport (IBAT) inhibitor approved under the brand name Bylvay ® in the U.S. as the first drug treatment option for patients 3 months of ...

Therefore, if a child presents in early infancy with cholestatic hepatitis with normal γGT, elevated serum bile acid concentrations (excluding bile acid synthesis defects) and without lymphoedema ...

Hepatitis B virus (HBV) infection is a leading cause of chronic liver diseases that spreads among individuals through blood ...