Herpes simplex virus (HSV), the viral agent causing human genital herpes, recurs easily and poses significant harm to patients, while also being associated with atherosc ...

Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

Bone development is the formation and growth of bones ... enables detailed analysis of bone and cartilage maturation. BMP signaling is important for multiple process, including craniofacial ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Key takeawaysUCLA researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a ...

Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone ... BMP signaling, which occurs only within the boundaries of the ...

The Wnt/β-catenin signaling pathway plays an important role in bone formation. Signaling is initiated by the binding of Wnt to a Frizzled receptor as well as a low-density lipoprotein receptor ...

The movie adaptation of Tomi Adeyemi's debut YA novel, Children of Blood and Bone, is officially on the horizon. After being years in the making, it looks like the literary phenomenon is finally ...

Institute of Environmental Engineering, National Yang Ming Chiao Tung University, Hsinchu city 30010, Taiwan ...

Skeletal remodeling is mediated by the integrated and tightly coupled actions of mechano-sensing osteocytes, bone-resorbing osteoclasts and bone-forming osteoblasts (Figure 1).