will cause or accelerate FOP’s characteristic heterotopic ossification — that is, the conversion of soft tissue to bone. Only once FOP is identified can efforts be made to avoid these events.
Most bones in our body contain bone marrow, but long bones, such as arms and legs, and flat bones, such as the skull, are formed through different developmental and ossification processes. The mouse ...
Our lab has developed a cell-based gene therapy system using adenoviral vectors for the rapid induction of bone formation for clinical applications including both spinal fusion and fracture repair, as ...