The latent HIV reservoir is a major barrier to HIV cure. Combining latency reversal agents (LRAs) with differing mechanisms of action such as AZD5582, a non-canonical NF-kB activator, and I-BET151, a ...
This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...
The case of CRISPR demonstrates how important it is to give scientists time to develop novel ... “the success of ‘science’ cannot be used as an argument for treating as yet unsolved problems in a ...
Background: CRISPR-based genetic medicines offer a promising “one and done” approach to improve cardiovascular health by lowering LDL-C. We performed a comparative analysis of different gene editing ...