In this paper, a CRISPR-based gene addition strategy at the CX3CR1 locus of human hematopoietic stem cells is proposed to efficiently generate microglia engineered for the regulated expression of ...

In this paper, a CRISPR-based gene addition strategy at the CX3CR1 locus of human hematopoietic stem cells is proposed to efficiently generate microglia engineered for the regulated expression of ...

Gerry Baker is Editor at Large of The Wall Street Journal. His weekly column for the editorial page, “Free Expression,” appears in The Wall Street Journal each Tuesday. Mr. Baker is also host ...

Apoe-deficient mouse brains: Displayed no fibrillar amyloid plaques and had increased levels of soluble Aβ aggregates. Human APOE isoforms in astrocytes: Expression in astrocytes alone induced ...

(e-f”) app-cx3cr1-cre mutant cortices treated with LPS at embryonic stages showed perturbed basement membrane and gaps at sites of ectopia (white arrows) at P0 (Laminin, green; DAPI, blue).

The tool we’re going to talk about today is called Expression Web 4, and no, it’s not the paid version. The software giant has released a free version of the tool. Now, we should point out ...

This article explores emotional regulation and the closely related issue of emotional expression, and introduces tools to manage and express feelings more successfully. Before you continue, we thought ...

Adult-born granular cells (abGCs) in microglia-depleted mice have lower spine density, but not spine size, compared to abGCs in WT control mice. Together these findings suggest that microglia have ...