Receptor pharmacology is the study of the interactions of receptors with drugs/pharmaceuticals and other xenobiotics. A basic tenet of receptor pharmacology is that a drug’s effect is directly ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In the early phase of Alzheimer’s disease, ...

发现SARS-CoV-2感染的心脏微血栓过程中，MYO1E high RASGEF1B high 单核细胞来源的巨噬细胞亚群通过激活趋化因子 CCL3、CCL5 促进免疫系统的过度激活并启动 ...

In addition, inhibition of two efferocytosis receptors, Axl and Timd4, abrogates proper wound repair. The results provide an atlas of cellular dynamics during the early stages of wound healing and ...

Here we identify DNA-dependent protein kinase (DNA-PK) as a DNA sensor that activates innate immunity. We show that DNA-PK acts as a pattern recognition receptor, binding cytoplasmic DNA and ...