The simultaneous inhibition of the transcription factors Myc and JunB could represent a pioneering therapeutic option for the ...

MYC is a transcription factor that plays relevant roles in cellular processes such as glycolysis, development, cell differentiation or proliferation. Recent research has associated the transcriptional ...

Melanoma is a type of cancer that originates from melanocytes, the cells responsible for producing skin pigment, and is known ...

It helps prevent cancer cell proliferation by taking control of the cell cycle via suppressing the expression ... which provides instructions to make a protein involved in development of teeth, bones ...

PCNSL relapse was histologically confirmed in October 2021, with expression of CD20, BCL2, BCL6, MUM1, and c-Myc ... T-cell therapy. The first question is whether the observed T-cell proliferation ...

15, 2024 — A team tests the protective effect of a fermented black garlic extract against inflammation and the progression of prostate cancer in a study conducted on human prostate cancer cell ...

Primary breast lymphoma (PBL) is an uncommon type of breast malignancy. Its clinical presentation and radiographic findings are non-specific and overlap with breast carcinoma. The treatment of PBL ...

Key mechanism of resistance to BRAF-targeted melanoma therapy discovered. Potential for developing new cancer therapies with high efficacy by regulating polyamine biosynthesis to suppress resistance.

Thus, an emerging strategy for the treatment of those conditions is to inhibit cellular proliferation by targeting cell cycle regulation. Here we will review the current understanding of the ...

The study demonstrated that CD12 suppresses prostate cancers, and its loss drives AR and myelocytomatosis proto-oncogene (MYC ... cellular proliferation and immune infiltration by T cells with ...