A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these ...
Alterations in genes such as CDKN2A, DEPDC5, RB1, and DMD are more frequent in advanced GISTs, and massive genomic rearrangement events like chromothripsis and kataegis contribute to tumor ...