Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...

The design principles dictating the spatio-temporal organisation of eukaryotic cells, and in particular the mechanisms controlling the self-organisation and dynamics of membrane-bound organelles such ...

What is the minimal set of cell-biological ingredients needed to generate a Golgi apparatus? The compositions of eukaryotic organelles arise through a process of molecular exchange via vesicle traffic ...