Inotuzumab Ozogamicin and Low-Intensity Chemotherapy in Older Patients With Newly Diagnosed CD22+ Philadelphia Chromosome–Negative B-Cell Precursor Acute Lymphoblastic Leukemia We enrolled 16 patients ...

Novartis NVS announced that the Committee for Medicinal Products for Human Use (“CHMP”) of the European Medicines Agency (EMA ...

CDK4–cyclin D1, CDK5–p35, His-tagged Erk1 and Erk2, protein kinase C isoforms, the catalytic subunit of cAPK, cGMP-dependent protein kinase, casein kinases 1 and 2, the insulin-receptor ...

A powerful, three-drug therapy for aggressive advanced breast cancer doubles the length of time before the cancer progresses, ...

Marinus Pharmaceuticals has reported that the Phase III TrustTSC trial of oral ganaxolone in treating seizures linked to ...

Image Credit: Kateryna Kon/Shutterstock.com In a recent study published in Cell Reports Medicine, researchers investigated whether loss of the cyclin-dependent kinase 12 (CDK12) gene drives ...

When this protein - cyclin-dependent kinase (CDK) - was suppressed, the treatment also prevented a change in the colour of their fur. This leaves the door open for scientists to help delay the ...

Presented clinical data for multiple assets across modalities, including bispecific antibody candidate BNT327/PM8002 and mRNA cancer vaccine ...

Comparatively, the ONCD drug library consisted of conventional cancer treatments, such as cyclin-dependent kinase (CDK) and receptor tyrosine kinase (RTK) inhibitors. A total of 130 different ...

We enrolled 16 patients with PMC in a single-arm personalized cancer therapy trial. For all patients, tumor tissue and/or circulating tumor DNA genomic profiling using next-generation sequencing and, ...