A new study led by Harvard Medical School researchers shed new light on how even a single defective copy of the ...

CRISPR-based gene-editing tools are being developed to correct specific defective sections of the genome to cure inherited genetic diseases, with some applications already in clinical trials. However, ...

Most cancers arise when breaks in a cell's DNA go undetected and unrepaired, allowing the damaged cell to churn out defective ...

After the genes have been tagged, Sleeping Beauty can introduce DNA into the gene’s chromosomes, and through experimentation, find a way to mend the defective gene. “It is the applied principle of ...

Generally, a single functioning copy of a gene is sufficient to ensure normal function even when the second copy is defective. Under this two-hit model, Brugge says, one normal copy of BRCA1 ought ...

They found that knocking out the gene in mice was lethal at the embryonic stage. "The embryos have many bone malformations in ...

A molar pregnancy, also known as a hydatidiform mole, is an abnormal human pregnancy with no embryo and an overgrowth of the ...

While your genes may nudge you toward sugary foods, understanding this genetic influence can empower healthier choices.

Large amounts of sugar can damage cells, causing chronic inflammation, which can lead to obesity, heart disease, diabetes, ...

including gene insertion (inserting DNA into a gene to cause expression/add function), elimination (removing a genome, e.g., ...

Autism-linked SHANK3 gene mutations disrupt not only neurons but also oligodendrocytes, essential for producing myelin, which ...