Neurons were transfected with Mito-DsRed, Halo-OPTN, and LAMP1-EGFP and mitophagy was induced. We identified OPTN-positive mitochondria and quantified the ratio of LAMP1-positive or LAMP1-negative ...
SNX6 is a ubiquitously expressed PX-BAR protein that plays important roles in retromer-mediated retrograde vesicular transport from endosomes. Here we report that CNS-specific Snx6 knockout mice ...