The term "alert and oriented" (AO) is a medical notation describing a person's level of consciousness and cognition (the ability to understand and learn through thought, experiences, and the senses).

School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China Department of Gynaecology and Obstetrics, Shanghai Key Laboratory ...

The selective turnover of mitochondria via autophagy, known as mitophagy, is a major quality control mechanism safeguarding eukaryotic cells, including highly specialized neurons in the mammalian ...

它对整个身体的细胞功能，尤其是大脑的细胞功能至关重要。它的合成发生在线粒体中，通过氧化磷酸化（OXPHOS）是一个复杂的，多步骤的过程。当这一过程中的一个或多个要素发生故障时，可能导致ATP产生不平衡或活性氧（ROS）过量产生。这可能导致包括蛋白 ...

The generation of ATP via increased rates of glycolysis rather than OXPHOS despite the presence of adequate oxygen levels and fully functioning mitochondria. This was first described by Otto Warburg ...

Its synthesis, which occurs in the mitochondria, through oxidative phosphorylation (OXPHOS) is a complex, multi-step process. When one or more of the elements of this process malfunction ...

(25) An alternative strategy involves the use of multidrug delivery systems to inhibit oxidative phosphorylation (OXPHOS), aiming to reduce hypoxia and enhance the effectiveness of PDT. Yet, the ...

The study provides compelling evidence suggesting that proliferative hematopoietic stem cells mainly use glycolysis (rather than mitochondrial OXPHOS or TCA cycle) as their primary energy source ...