The main oxidative reaction in mitochondria is called oxidative phosphorylation (OXPHOS), the process through which chemical energy is generated in the form of the molecule ATP. In reductive ...

School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China Department of Gynaecology and Obstetrics, Shanghai Key Laboratory ...

The selective turnover of mitochondria via autophagy, known as mitophagy, is a major quality control mechanism safeguarding eukaryotic cells, including highly specialized neurons in the mammalian ...

它对整个身体的细胞功能，尤其是大脑的细胞功能至关重要。它的合成发生在线粒体中，通过氧化磷酸化（OXPHOS）是一个复杂的，多步骤的过程。当这一过程中的一个或多个要素发生故障时，可能导致ATP产生不平衡或活性氧（ROS）过量产生。这可能导致包括蛋白 ...