Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Barrier-to-autointegration factor (BAF) is an ...

Many people are aware that BRCA2 gene mutations are associated with an increased risk of breast cancer, but these mutations have also been linked with ovarian cancer, pancreatic cancer, prostate ...

Among families that fit these conditions, about 25% to 40% will have a CDH1 gene mutation. Families with multiple cases of diffuse stomach cancer, as well as patients diagnosed with diffuse stomach ...

They discovered that some genetic mutations reduced the function of the ion channel by up to 90%, resulting in a 13.3-fold greater risk of major cardiac events (arrhythmia, sudden death).

Protein behavior can be predicted with simple math Mutations affect protein stability following remarkably simple rules Date: September 25, 2024 Source: Center for Genomic Regulation Summary ...

A rare cause of hereditary cognitive decline known as CSF1R-Related Disorder (CSF1R-RD) gets its name from mutations in the CSF1R gene, discovered by Mayo Clinic. Memory loss occurs as the ...

KRAS is the most mutated gene in cancer with mutations occurring in 17%–25% of all cancers, affecting millions of patients worldwide. It plays a crucial role in tumor growth, as it is important ...

What Is the MTHFR Gene Mutation? The MTHFR gene mutation is a variation in the MTHFR gene. This gene normally tells your body how to make the MTHFR protein. You need this protein to process folate ...

Yellow mosaic disease (YMD) is one of the major devastating diseases that severely hampers soybean production. The disease is mainly caused by the mungbean yellow mosaic India virus (MYMIV), mungbean ...

Here, multi-microsecond molecular dynamics is combined with solution NMR and graph theory-derived models to probe the allosteric role of key specificity-enhancing mutations. We show that mutations ...